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Guardian One® 45mg Lufenuron & Nitenpyram monthly for Small Dogs 2 - 10 Lbs

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Guardian One® 45mg Lufenuron & Nitenpyram monthly for Small Dogs 2 - 10 Lbs
Guardian One® 45mg Lufenuron & Nitenpyram monthly for Small Dogs 2 - 10 Lbs
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1 unit
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Guardian One® 45mg Lufenuron & Nitenpyram monthly for Small Dogs 2 - 10 Lbs
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Pet owners love Guardian products for a reason!

  • 11.4mg of Nitenpyram and 45mg of USP grade Lufenuron carefully blended with premium meat in a compact clear gelcap
  • For Small Dogs 2 - 10 Lbs
  • Nitenpyram starts working in 30 minutes & Lufenuron protects for 30 days
  • Guardian One is given once every 30 days and is an excellent monthly pet product
  • No Preservatives and No Artificial Flavors
  • 2 All Natural, Real Smoked Meats 
  • Lufenuron and Nitenpyram have been available in Canada and the USA since 1995, and are currently marketed in over 30 countries worldwide.
  • A must have product for spring and summer!
  • An easy to use gelcap makes our products super flexible to give, even for the most resistant cat or dog!
  • Nitenpyram is the gold standard in pet supply products. 
  • Lufenuron and Nitenpyram are both gentle and time tested.
  • We never want price to a be a barrier between pet's getting the products that make their lives better. 


Expiration date:

Guardian ONLY uses all natural, restaurant quality cuts of meat in their products. Guardian products contain no preservatives and we only use oak or hickory fired smoke to preserve our dried meats. They can last almost indefinitely refrigerated and 2 years or longer in a room temperature drawer. The airtight bottle cap and gelcaps locking design reduce air penetration dramatically compared to tablets and soft chews.


  • Guardian One with Lufenuron + Nitenpyram should be given once a month.
  • This product may be given as often as needed following the initial monthly dose.
  • Guardian One with Lufenuron + Nitenpyram should NOT be given to dogs with a history of seizures or kidney problems.
  • This product should be given on a full stomach to ensure optimal absorption of Lufenuron.
  • The Lufenuron and Nitenpyram in this product is for all healthy dogs and puppies weighing between 2 and 10 pounds and over 8 weeks of age.
  • This product can be used with pregnant or nursing dogs.
  • The gelcap separates the Lufenuron and Nitenpyram from your dog's taste buds and scent receptors and also helps avoid the bitter reaction common in many pet medications and supplements on the market in tablet or chewable form.
  • If you're not sure that your dog or cat consumed the pill or it's contents, you may give another pill.
  • The gelcap delivery method gives you a more flexible feeding window. The gelcap will delay the release of the Lufenuron by a few minutes compared to a tablet or chew.
  • Our gelcap products benefit from our Flavor Infusion technology. We infuse the outer gelcap wall with the scent of the meat inside. It's a delicate process and requires a proprietary manufacturing method. This does NOT flavor the gelcap, it only adds scent for ultra-discerning pets.
  • Guardian's Gelcap products are designed to make it easy to use even with super finicky pets!
  • Guardian's gelcap products are designed to make your life and your pet's life much better. Your pets deserve to live in a utopia! We hope you'll never dread spring and summer again!

Product Reviews (4)

  • 5

    works splendid

    I use this and it keeps the fleas away. Buying online is a little cheaper than buying in stores

  • 5

    Great for rescues!

    Were a small rescue and weve been using Guardian products for 5+ years after their sales rep stopped by our rescue. They even gave us a rescue discount code saving us money. I cant say enough good things about Guardian, they truly are awesome and their products work!

  • 5

    for my cats

    I use this for my cats to prevent fleas. It works great. Just empty the capsules over their food and you're done!

  • 5

    love them

    These work wonderfully! I regularly share them with my non-profit foster animals to treat for fleas at an affordable rate.